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From: "Wiley" <e-service@info.wiley.com>
Subject: Learn from experts: Managing sequence variants in protein therapeutics
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                                      </tbody>
                                    </table>
                                  </td>
                                </tr>
                              </tbody>
                            </table>
                          </td>
                        </tr>
                      </tbody>
                    </table>
                  </td>
                </tr>
              </tbody>
            </table>
            <table style=3D"max-width:600px;min-width:300px;margin:0 auto;"=
 class=3D"row row-5" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
                <tr>
                  <td style=3D"background:#FFFFFF;">
                    <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"=
0">
                      <tbody>
                        <tr>
                          <td>
                            <table width=3D"100%" cellspacing=3D"0" cellpad=
ding=3D"0">
                              <tbody>
                                <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px">
                                    <table class=3D"tolkien-column tolkien-=
column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
round:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-=
serif !important;font-size:12px;color:#383838;max-width:100%;width:100%;wid=
th:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:=
480px;min-width:-webkit-calc(100%);min-width:calc(100%);" cellspacing=3D"0"=
 cellpadding=3D"0">
                                      <tbody>
                                        <tr>
                                          <td style=3D"height:20px;backgrou=
nd-color:transparent;line-height:18px;" class=3D"elq-space-cell cell cell-0=
">
                                            <div style=3D"height:20px;displ=
ay:none;">&nbsp;</div>
                                          </td>
                                        </tr>
                                        <tr>
                                          <td style=3D"background-color:tra=
nsparent;line-height:18px;padding:0px 30px 0px 30px;" class=3D"elq-text-cel=
l cell cell-1">
                                            <div style=3D"display:inline-bl=
ock;width:100%;">
                                              <h1>You=92re invited</h1>
                                            </div>
                                          </td>
                                        </tr>
                                      </tbody>
                                    </table>
                                  </td>
                                </tr>
                              </tbody>
                            </table>
                          </td>
                        </tr>
                      </tbody>
                    </table>
                  </td>
                </tr>
              </tbody>
            </table>
            <table style=3D"max-width:600px;min-width:300px;margin:0 auto;"=
 class=3D"row row-6" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
                <tr>
                  <td style=3D"background:#FFFFFF;">
                    <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"=
0">
                      <tbody>
                        <tr>
                          <td>
                            <table width=3D"100%" cellspacing=3D"0" cellpad=
ding=3D"0">
                              <tbody>
                                <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px">
                                    <table class=3D"tolkien-column tolkien-=
column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
round:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-=
serif !important;font-size:12px;color:#383838;max-width:100%;width:100%;wid=
th:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:=
480px;min-width:-webkit-calc(100%);min-width:calc(100%);" cellspacing=3D"0"=
 cellpadding=3D"0">
                                      <tbody>
                                        <tr>
                                          <td style=3D"background-color:tra=
nsparent;line-height:18px;padding:10px 10px 10px 30px;" class=3D"elq-text-c=
ell cell cell-0">
                                            <div style=3D"display:inline-bl=
ock;width:100%;">
                                              <div style=3D"line-height: 21=
px;" data-lineheight=3D"1.5"><span style=3D"font-size: 14px;">Dive into the=
 world of biotherapeutics with our upcoming webinar! We'll explore the impa=
ct of sequence variants on protein therapeutics and reveal cutting-edge det=
ection methods. Learn from real-world case studies and gain valuable insigh=
ts that will enhance your understanding and expertise.
<br/><br/>
What to expect:

</span></div>
                                            </div>
                                          </td>
                                        </tr>
                                        <tr>
                                          <td style=3D"height:10px;backgrou=
nd-color:transparent;line-height:18px;" class=3D"elq-space-cell cell cell-1=
">
                                            <div style=3D"height:10px;displ=
ay:none;">&nbsp;</div>
                                          </td>
                                        </tr>
                    
                    <tr>
                  <td style=3D"background:#FFFFFF;">
                    
                            <table width=3D"100%" cellspacing=3D"0" cellpad=
ding=3D"0">
                              <tbody>
                                <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px; padding-bottom:10px;">
                                    <table class=3D"tolkien-column tolkien-=
column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
round:transparent;table-layout:fixed;font-family:Arial, Helvetica, sans-ser=
if;font-size:12px;max-width:100%;width:100%;width:-webkit-calc(230400px - 4=
8000%);width:calc(230400px - 48000%);min-width:480px;min-width:-webkit-calc=
(100%);min-width:calc(100%);" cellspacing=3D"0" cellpadding=3D"0">
                                      <tbody>
                                        <tr>
                      <td class=3D"out_bul" style=3D"text-align: right; lin=
e-height: 22px;padding-left:10px;padding-top:4px;font-size: 20px;font-weigh=
t:bold;" width=3D"10%" valign=3D"top">&bull;</td>
                      <td class=3D"" style=3D"padding:2px 20px 0px 20px; wi=
dth:100% !important; font-size: 14px;font-family: 'Open Sans', Arial, sans-=
serif;color: #383838; line-height: 22px;" width=3D"94%" valign=3D"top" bgco=
lor=3D"#FFFFFF"><div style=3D"line-height: 24px;" data-lineheight=3D"1.5"><=
span style=3D"font-size: 14px;">Understand the impact of sequence variants =
on drug efficacy, stability, and immune responses.</span></div></td>
                    </tr>
          <tr>
                      <td class=3D"out_bul" style=3D"text-align: right; lin=
e-height: 22px;padding-left:10px;padding-top:4px;font-size: 20px;font-weigh=
t:bold;" width=3D"10%" valign=3D"top">&bull;</td>
                      <td class=3D"" style=3D"padding:2px 20px 0px 20px; wi=
dth:100% !important; font-size: 14px;font-family: 'Open Sans', Arial, sans-=
serif;color: #383838; line-height: 22px;" width=3D"94%" valign=3D"top" bgco=
lor=3D"#FFFFFF"><div style=3D"line-height: 24px;" data-lineheight=3D"1.5"><=
span style=3D"font-size: 14px;">Discover detection methods using icIEF-UV/M=
S and EAD-enabled LC/MS techniques.</span></div></td>
                    </tr>
          <tr>
                      <td class=3D"out_bul" style=3D"text-align: right; lin=
e-height: 22px;padding-left:10px;padding-top:4px;font-size: 20px;font-weigh=
t:bold;" width=3D"10%" valign=3D"top">&bull;</td>
                      <td class=3D"" style=3D"padding:2px 20px 0px 20px; wi=
dth:100% !important; font-size: 14px;font-family: 'Open Sans', Arial, sans-=
serif;color: #383838; line-height: 22px;" width=3D"94%" valign=3D"top" bgco=
lor=3D"#FFFFFF"><div style=3D"line-height: 24px;" data-lineheight=3D"1.5"><=
span style=3D"font-size: 14px;">Explore a real-world case study on identify=
ing and mitigating a sequence variant.</span></div></td>
                    </tr>
          
         
              
                                      </tbody>
                                    </table>
                                  </td>
                                </tr>
                              </tbody>
                            </table>
          </td>
                </tr>  
                    
                      
                                          
                                        </tbody>
                                      </table>
                    
                                    </td>
                                  </tr>
                                  
                                  
                               
                      
                                          
                                        </tbody>
                                      </table>
                                    </td>
                                  </tr>
                  
                  <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px">
                                    <table class=3D"tolkien-column tolkien-=
column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
round:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-=
serif !important;font-size:12px;color:#383838;max-width:100%;width:100%;wid=
th:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:=
480px;min-width:-webkit-calc(100%);min-width:calc(100%);" cellspacing=3D"0"=
 cellpadding=3D"0">
                                      <tbody>
                                        <tr>
                                          <td style=3D"background-color:tra=
nsparent;line-height:18px;padding:10px 30px 10px 30px;" class=3D"elq-text-c=
ell cell cell-0">
                                            <div style=3D"display:inline-bl=
ock;width:100%;">
                                              <div style=3D"line-height: 21=
px;" data-lineheight=3D"1.5"><span style=3D"font-size: 14px;">Ready to get =
started=3F Register now to secure your spot!
</span></div>
                                            </div>
                                          </td>
                                        </tr>
                                       
                    
                      
                                          
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                                      </table>
                    
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                                  </tr>
                    
                    <tr>
              <td>
              <table style=3D"max-width:600px;min-width:300px;margin:0 auto=
;" class=3D"row row-6" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
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ding=3D"0">
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nsparent;line-height:18px;padding:10px 30px 10px 30px;" class=3D"elq-button=
-cell cell cell-2">
                                            <div style=3D"text-align:center=
;font-family: 'Open Sans', Arial, sans-serif !important;">
                                              <div>

                                                <!--[if gte mso 9]>
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rgettype=3D"nohyperlink" data-targetname=3D"" style=3D"text-decoration: non=
e;">
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ial; table-layout: fixed;">
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reak-word; color: #fff; text-align: center; background-color: #123d80; padd=
ing: 15px 30px 15px 30px; border-radius: 0px; border: 2px none #000000;">
        <![endif]-->
                                              </div><a href=3D"https://t6.i=
nfo.wiley.com/r/=3Fid=3Dh1e1d7559-081a-4f19-9457-5286a4e27041,7cad7b,4b2989=
" target=3D"_blank" title=3D"" data-targettype=3D"nohyperlink" data-targetn=
ame=3D"" style=3D"text-decoration:none;vertical-align:middle;word-wrap:brea=
k-word;overflow-wrap:break-word;color:#fff;text-align:center;background-col=
or:#123d80;padding:15px 30px 15px 30px;border-radius:0;display:inline-block=
;max-width:100%;width:auto;"><span style=3D"background-color:#123d80;cursor=
:pointer;text-decoration:none;user-select:none;"><span style=3D"direction: =
ltr;"><strong style=3D"font-size: 16px; font-family: 'Open Sans', Arial, sa=
ns-serif !important; color: rgb(255, 255, 255);">REGISTER NOW</strong></spa=
n></span></a>
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r></tbody></table></a><![endif]-->
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                </tr>
              </tbody>
            </table>
            
           
      
            <table style=3D"max-width:600px;min-width:300px;margin:0 auto;"=
 class=3D"row row-16" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
                <tr>
                  <td style=3D"background:#FFFFFF;">
                    <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"=
0">
                      <tbody>
                        <tr>
                          <td>
                            <table width=3D"100%" cellspacing=3D"0" cellpad=
ding=3D"0">
                              <tbody>
                                <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px">
                                    <table class=3D"tolkien-column tolkien-=
column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
round:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-=
serif !important;font-size:12px;color:#383838;max-width:100%;width:100%;wid=
th:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:=
480px;min-width:-webkit-calc(100%);min-width:calc(100%);" cellspacing=3D"0"=
 cellpadding=3D"0">
                                      <tbody>
                                        <tr>
                                          <td style=3D"height:10px;backgrou=
nd-color:transparent;line-height:18px;" class=3D"elq-space-cell cell cell-0=
">
                                            <div style=3D"height:10px;displ=
ay:none;">&nbsp;</div>
                                          </td>
                                        </tr>
                                        <tr>
                                          <td style=3D"background-color:tra=
nsparent;line-height:18px;padding:0px 30px 0px 30px;" class=3D"elq-text-cel=
l cell cell-1">
                                            <div style=3D"display:inline-bl=
ock;width:100%;">
                                              <h1>Speaker information</h1>
                                            </div>
                                          </td>
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            <table style=3D"max-width:600px;min-width:300px;margin:0 auto;"=
 class=3D"row row-17" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
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                  <td style=3D"background:#FFFFFF;">
                    <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"=
0">
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ding=3D"0">
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gn:top;font-size:0px">
                                    <table class=3D"tolkien-column tolkien-=
column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
round:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-=
serif !important;font-size:12px;color:#383838;max-width:100%;width:100%;wid=
th:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:=
480px;min-width:-webkit-calc(100%);min-width:calc(100%);" cellspacing=3D"0"=
 cellpadding=3D"0">
                                      <tbody>
                                        <tr>
                                          <td style=3D"height:10px;backgrou=
nd-color:transparent;line-height:18px;" class=3D"elq-space-cell cell cell-0=
">
                                            <div style=3D"height:10px;displ=
ay:none;">&nbsp;</div>
                                          </td>
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      <table style=3D"max-width:600px;min-width:300px;margin:0 auto;" class=
=3D"row row-18" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
                <tr>
                  <td style=3D"background:#FFFFFF;">
                    <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"=
0">
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                        <tr>
                          <td>
                            <table width=3D"100%" cellspacing=3D"0" cellpad=
ding=3D"0">
                              <tbody>
                                <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px">
                                    <table class=3D"tolkien-column tolkien-=
column-3 col col-0" style=3D"vertical-align:top;display:inline-table;backgr=
ound:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-s=
erif !important;font-size:12px;color:#383838;max-width:100%;width:25%;width=
:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:12=
0px;min-width:-webkit-calc(25%);min-width:calc(25%);" cellspacing=3D"0" cel=
lpadding=3D"0">
                                      <tbody>
                                        <tr>
                                          <td class=3D"elq-image-cell  cell=
 cell-0" style=3D"background-color:transparent;line-height:0;padding:0px 0p=
x 30px 30px;text-align:left;">
                                            <!--[if mso]><table width=3D"10=
0%" style=3D"width:100%;height:auto;max-width:120px" cellpadding=3D"0" cell=
spacing=3D"0" border=3D"0"><tr><td style=3D"padding-right: 0px; padding-lef=
t: 0px;" align=3D"left"><![endif]-->
                                            <img src=3D"https://res6.info.w=
iley.com/res/tracking/979460_KristenNields_Speaker.jpg" style=3D"width:100%=
;height:auto;max-width:135px;" width=3D"120" height=3D"auto">
                                            <!--[if mso]></td></tr></table>=
<![endif]-->
                                          </td>
                                        </tr>
                                      </tbody>
                                    </table>
                                    <!--[if (gte mso 9)|(IE)]></td><td widt=
h=3D"75%" style=3D"text-align:left;vertical-align:top;font-size:0px"><![end=
if]-->
                                    <table class=3D"tolkien-column tolkien-=
column-9 col col-1" style=3D"vertical-align:top;display:inline-table;backgr=
ound:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-s=
erif !important;font-size:12px;color:#383838;max-width:100%;width:75%;width=
:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:36=
0px;min-width:-webkit-calc(75%);min-width:calc(75%);" cellspacing=3D"0" cel=
lpadding=3D"0">
                                      <tbody>
                                        <tr>
                                          <td style=3D"background-color:tra=
nsparent;line-height:18px;padding:0px 30px 30px 30px;" class=3D"elq-text-ce=
ll cell cell-0">
                                            <div style=3D"display:inline-bl=
ock;width:100%;">
                                              <div style=3D"line-height: 21=
px;" data-lineheight=3D"1.5"><strong style=3D"color: rgb(0, 0, 0); font-siz=
e: 14px;">Kristen Nields, Principal Scientist<br/>
Johnson & Johnson Innovative Medicine

</strong></div>
                                              <div style=3D"line-height: 21=
px;" data-lineheight=3D"1.5"><span style=3D"color: rgb(0, 0, 0); font-size:=
 14px;">Kristen Nields is the Principal Scientist in the Cell and Developab=
ility Group at Johnson & Johnson Innovative Medicine with 20+ years of expe=
rience in the biopharma industry. She specializes in bridging mass spectrom=
etry and product quality functions to enhance communication. Kristen is rec=
ognized for developing innovative analytical methods within the Johnson & J=
ohnson organization to close product knowledge gaps.
</span></div>
                                            </div>
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       <table style=3D"max-width:600px;min-width:300px;margin:0 auto;" clas=
s=3D"row row-18" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
                <tr>
                  <td style=3D"background:#FFFFFF;">
                    <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"=
0">
                      <tbody>
                        <tr>
                          <td>
                            <table width=3D"100%" cellspacing=3D"0" cellpad=
ding=3D"0">
                              <tbody>
                                <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px">
                                    <table class=3D"tolkien-column tolkien-=
column-3 col col-0" style=3D"vertical-align:top;display:inline-table;backgr=
ound:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-s=
erif !important;font-size:12px;color:#383838;max-width:100%;width:25%;width=
:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:12=
0px;min-width:-webkit-calc(25%);min-width:calc(25%);" cellspacing=3D"0" cel=
lpadding=3D"0">
                                      <tbody>
                                        <tr>
                                          <td class=3D"elq-image-cell  cell=
 cell-0" style=3D"background-color:transparent;line-height:0;padding:0px 0p=
x 30px 30px;text-align:left;">
                                            <!--[if mso]><table width=3D"10=
0%" style=3D"width:100%;height:auto;max-width:120px" cellpadding=3D"0" cell=
spacing=3D"0" border=3D"0"><tr><td style=3D"padding-right: 0px; padding-lef=
t: 0px;" align=3D"left"><![endif]-->
                                            <img src=3D"https://res6.info.w=
iley.com/res/tracking/979460_RileySchaefer_Speaker.jpg" style=3D"width:100%=
;height:auto;max-width:135px;" width=3D"120" height=3D"auto">
                                            <!--[if mso]></td></tr></table>=
<![endif]-->
                                          </td>
                                        </tr>
                                      </tbody>
                                    </table>
                                    <!--[if (gte mso 9)|(IE)]></td><td widt=
h=3D"75%" style=3D"text-align:left;vertical-align:top;font-size:0px"><![end=
if]-->
                                    <table class=3D"tolkien-column tolkien-=
column-9 col col-1" style=3D"vertical-align:top;display:inline-table;backgr=
ound:transparent;table-layout:fixed;font-family: 'Open Sans', Arial, sans-s=
erif !important;font-size:12px;color:#383838;max-width:100%;width:75%;width=
:-webkit-calc(230400px - 48000%);width:calc(230400px - 48000%);min-width:36=
0px;min-width:-webkit-calc(75%);min-width:calc(75%);" cellspacing=3D"0" cel=
lpadding=3D"0">
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                                          <td style=3D"background-color:tra=
nsparent;line-height:18px;padding:0px 30px 30px 30px;" class=3D"elq-text-ce=
ll cell cell-0">
                                            <div style=3D"display:inline-bl=
ock;width:100%;">
                                              <div style=3D"line-height: 21=
px;" data-lineheight=3D"1.5"><strong style=3D"color: rgb(0, 0, 0); font-siz=
e: 14px;">Riley Schaefer, Co-Op Scientist II<br/>
Johnson & Johnson Innovative Medicine


</strong></div>
                                              <div style=3D"line-height: 21=
px;" data-lineheight=3D"1.5"><span style=3D"color: rgb(0, 0, 0); font-size:=
 14px;">Riley Schaefer is a recent honors graduate from St. Joseph=92s Univ=
ersity with a B.S. in Biochemistry. He currently works as the Analytical Ce=
ll Engineering & Development Co-Op at Johnson & Johnson Innovative Medicine=
. His focus is on developing analytical methods to assess the biophysical p=
roduct quality of monoclonal and multi-specific antibodies for the purpose =
of engineering an array of manufacturing cell lines.
</span></div>
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0">
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ding=3D"0">
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gn:top;font-size:0px">
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column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
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serif !important;font-size:12px;color:#383838;max-width:100%;width:100%;wid=
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480px;min-width:-webkit-calc(100%);min-width:calc(100%);" cellspacing=3D"0"=
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ock;width:100%;">
                                              <div style=3D"line-height: 21=
px;" data-lineheight=3D"1.5"><strong style=3D"font-size: 14px;">This virtua=
l seminar has been made possible through sponsorship from Sciex.</strong></=
div>
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