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From: "Wiley" <e-service@info.wiley.com>
Subject: Focus on adeno-associated viruses (AAVs)
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0xN2I5ODA4Yy1jNzkwLTQ0OTQtODNiOC05Y2MzZTVhMTYwMmImdXRtX2NhbXBhaWduPTE2OTQ4M=
TkmdXRtX3NvdXJjZT1hZG9iZUVtYWlsJnV0bV9tZWRpdW09RW1haWwmdXRtX3Rlcm09ODU1NzE2=
LUIyQkFTLUxpc3RfUmVnLTE2JnV0bV9jb250ZW50PUVNMl84NTU3MTYtQjJCQVMtTGlzdF9SZWd=
fRXVyb3Bl&s=3DYgEdxTbZne2LHemTsDFKKLk7VivvrQernichtH3iJTo" data-targettype=
=3D"webpage"><img src=3D"https://res6.info.wiley.com/res/tracking/EM1_85571=
6_Bannerimage.png" style=3D"width:100%;height:auto;max-width:600px;border:n=
one;" width=3D"600" height=3D"auto"></a>
                                            <!--[if mso]></td></tr></table>=
<![endif]-->
                                          </td>
                                        </tr>
                    
                    
                    
                                      </tbody>
                                    </table>
              
              
                          </td>
                        </tr>
                      </tbody>
                    </table>
                  </td>
                </tr>
              </tbody>
            </table>
            
      
        <table style=3D"max-width:600px;min-width:300px;margin:0 auto;" cla=
ss=3D"row row-5" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
                <tr>
                  <td style=3D"background:#FFFFFF;">
                    <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"=
0">
                      <tbody>
                        <tr>
                          <td>
                            <table width=3D"100%" cellspacing=3D"0" cellpad=
ding=3D"0">
                              <tbody>
                                <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px">
                                    <table class=3D"tolkien-column tolkien-=
column-9 col col-0" style=3D"vertical-align:top;display:inline-table;backgr=
ound:transparent;table-layout:fixed;font-family:Arial, Helvetica, sans-seri=
f;font-size:12px;color:#383838;max-width:100%;width:65%;width:-webkit-calc(=
230400px - 48000%);width:calc(230400px - 48000%);min-width:360px;min-width:=
-webkit-calc(65%);min-width:calc(65%);" cellspacing=3D"0" cellpadding=3D"0"=
>
                                      <tbody>
                                        
                                      <tr>
                                          <td style=3D"background-color:tra=
nsparent;line-height:18px;padding:20px 20px 0px 30px;" class=3D"elq-text-ce=
ll cell cell-2">
                                            <div style=3D"display:inline-bl=
ock;width:100%;">
                                              <div style=3D"line-height: 21=
px;" data-lineheight=3D"1.5"><span style=3D"font-size: 14px;">Read this com=
prehensive overview of the emergence of Adeno-associated viruses (AAVs) as =
vital tools in gene therapy due to their ability to deliver genetic materia=
l safely and efficiently. Discover the advancements in production, characte=
rization, and purification processes and the future prospects of AAV techno=
logy in therapeutic applications.
                                            </div>
                                          </td>
                                        </tr>
                    <tr>
                    <td style=3D"background-color:transparent;line-height:1=
8px;padding:10px 20px 10px 30px;" class=3D"elq-text-cell cell cell-2">
                       <div style=3D"display:inline-block;width:100%;">
                       <div style=3D"line-height: 21px;" data-lineheight=3D=
"1.5"><span style=3D"font-size: 14px;color: #383838;"><br>What you will lea=
rn: 
</div>
                                          </td>
                 </tr>
         
         <tr>
                  <td style=3D"background:#FFFFFF;">
                    
                            
          </td>
                </tr>
        
          
                
                                        
                                        <!-- <![endif]-->
                                      </tbody>
                                    </table>
                                    <!--[if (gte mso 9)|(IE)]></td><td widt=
h=3D"25%" style=3D"text-align:left;vertical-align:top;font-size:0px"><![end=
if]-->
                                    <table class=3D"tolkien-column tolkien-=
column-3 col col-1" style=3D"vertical-align:top;display:inline-table;backgr=
ound:transparent;table-layout:fixed;font-family:Arial, Helvetica, sans-seri=
f;font-size:12px;color:#383838;max-width:100%;width:35%;width:-webkit-calc(=
230400px - 48000%);width:calc(230400px - 48000%);min-width:120px;min-width:=
-webkit-calc(35%);min-width:calc(35%);" cellspacing=3D"0" cellpadding=3D"0"=
>
                                      <tbody>
                                        
                                        <tr>
                                          <td class=3D"elq-image-cell  cell=
 cell-1" style=3D"background-color:transparent;line-height:0;padding:20px 2=
0px 0px 0px;text-align:center;">
                                            <!--[if mso]><table width=3D"10=
0%" style=3D"width:100%;height:auto;max-width:150px" cellpadding=3D"0" cell=
spacing=3D"0" border=3D"0"><tr><td style=3D"padding-right: 0px; padding-lef=
t: 0px;" align=3D"center"><![endif]-->
                                             <a target=3D"_blank" title=3D"=
Cover" href=3D"https://t6.info.wiley.com/r/=3Fid=3Dh17b9808c-c790-4494-83b8=
-9cc3e5a1602b,7a4a97,485190&e=3DcmVjSWQ9QHk2YkdZdTA4MEdpTHE5NjNQUEExOHdyMEl=
kbHcxemRjT1FNaXQ2Q3RQZ3JTdnpUVmV1U0o1MlhKbVB0ejlnbVEmY2lkPURNMzM5OTU5JmJpZD=
0xN2I5ODA4Yy1jNzkwLTQ0OTQtODNiOC05Y2MzZTVhMTYwMmImdXRtX2NhbXBhaWduPTE2OTQ4M=
TkmdXRtX3NvdXJjZT1hZG9iZUVtYWlsJnV0bV9tZWRpdW09RW1haWwmdXRtX3Rlcm09ODU1NzE2=
LUIyQkFTLUxpc3RfUmVnLTE2JnV0bV9jb250ZW50PUVNMl84NTU3MTYtQjJCQVMtTGlzdF9SZWd=
fRXVyb3Bl&s=3DDiLx29-o6uQ-w4XUKdXNh2hIGFzMdpspZHFsjh_qIk8" data-targettype=
=3D"webpage"><img src=3D"https://res6.info.wiley.com/res/tracking/855716_EM=
1_BookCover.jpg" style=3D"width:100%;height:auto;max-width:150px;" width=3D=
"150" height=3D"auto"></a>
                                            <!--[if mso]></td></tr></table>=
<![endif]-->
                                          </td>
                                        </tr>
                                      </tbody>
                                    </table>
                                  </td>
                                </tr>
                              </tbody>
                            </table>
                          </td>
                        </tr>
                      </tbody>
                    </table>
                  </td>
                </tr>
              </tbody>
            </table>
      
       <table style=3D"max-width:600px;min-width:300px;margin:0 auto;" clas=
s=3D"row row-22" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
                <tr>
                  <td style=3D"background:#FFFFFF;">
          <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
                              <tbody>
                                <tr>
                                  <td style=3D"text-align:left;vertical-ali=
gn:top;font-size:0px; padding-bottom:10px;">
                                    <table class=3D"tolkien-column tolkien-=
column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
round:transparent;table-layout:fixed;font-family:Arial, Helvetica, sans-ser=
if;font-size:12px;max-width:100%;width:100%;width:-webkit-calc(230400px - 4=
8000%);width:calc(230400px - 48000%);min-width:480px;min-width:-webkit-calc=
(100%);min-width:calc(100%);" cellspacing=3D"0" cellpadding=3D"0">
                                      <tbody>
                                        <tr>
                      <td class=3D"out_bul" style=3D"text-align: right; lin=
e-height: 22px;padding-left:10px;padding-top:4px;font-size: 20px;font-weigh=
t:bold;" width=3D"10%" valign=3D"top">&bull;</td>
                      <td class=3D"" style=3D"padding:2px 20px 0px 20px; wi=
dth:100% !important; font-size: 14px;font-family: 'Open Sans', Arial, sans-=
serif;color: #383838; line-height: 22px;" width=3D"94%" valign=3D"top" bgco=
lor=3D"#FFFFFF"><div style=3D"line-height: 24px;" data-lineheight=3D"1.5"><=
span style=3D"font-size: 14px;"><b>Stability & Delivery:</b> Enhance AAV st=
ability and delivery with innovative shielding techniques.</span></div></td=
>
                    </tr>
          <tr>
                      <td class=3D"out_bul" style=3D"text-align: right; lin=
e-height: 22px;padding-left:10px;padding-top:4px;font-size: 20px;font-weigh=
t:bold;" width=3D"10%" valign=3D"top">&bull;</td>
                      <td class=3D"" style=3D"padding:2px 20px 0px 20px; wi=
dth:100% !important; font-size: 14px;font-family: 'Open Sans', Arial, sans-=
serif;color: #383838; line-height: 22px;" width=3D"94%" valign=3D"top" bgco=
lor=3D"#FFFFFF"><div style=3D"line-height: 24px;" data-lineheight=3D"1.5"><=
span style=3D"font-size: 14px;"><b>Transcriptomics:</b> Discover molecular =
signatures for rAAV production.</span></div></td>
                    </tr>
          <tr>
                      <td class=3D"out_bul" style=3D"text-align: right; lin=
e-height: 22px;padding-left:10px;padding-top:4px;font-size: 20px;font-weigh=
t:bold;" width=3D"10%" valign=3D"top">&bull;</td>
                      <td class=3D"" style=3D"padding:2px 20px 0px 20px; wi=
dth:100% !important; font-size: 14px;font-family: 'Open Sans', Arial, sans-=
serif;color: #383838; line-height: 22px;" width=3D"94%" valign=3D"top" bgco=
lor=3D"#FFFFFF"><div style=3D"line-height: 24px;" data-lineheight=3D"1.5"><=
span style=3D"font-size: 14px;"><b>mRNA-Sequencing:</b> In-depth analysis o=
f cell lines during gene therapy processes.</span></div></td>
                    </tr>
          <tr>
                      <td class=3D"out_bul" style=3D"text-align: right; lin=
e-height: 22px;padding-left:10px;padding-top:4px;font-size: 20px;font-weigh=
t:bold;" width=3D"10%" valign=3D"top">&bull;</td>
                      <td class=3D"" style=3D"padding:2px 20px 0px 20px; wi=
dth:100% !important; font-size: 14px;font-family: 'Open Sans', Arial, sans-=
serif;color: #383838; line-height: 22px;" width=3D"94%" valign=3D"top" bgco=
lor=3D"#FFFFFF"><div style=3D"line-height: 24px;" data-lineheight=3D"1.5"><=
span style=3D"font-size: 14px;"><b>Purification:</b> Simplified anion excha=
nge techniques for separating full and empty AAV capsids.</span></div></td>
                    </tr>
              
                                      </tbody>
                                    </table>
                                  </td>
                                </tr>
                              </tbody>
                            </table>
                    
                  </td>
                </tr>
              </tbody>
            </table>
      
            <table style=3D"max-width:600px;min-width:300px;margin:0 auto;"=
 class=3D"row row-6" width=3D"100%" cellspacing=3D"0" cellpadding=3D"0">
              <tbody>
                <tr>
                  <td style=3D"background:#FFFFFF;">
                    <table width=3D"100%" cellspacing=3D"0" cellpadding=3D"=
0">
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ding=3D"0">
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lign:top;font-size:0px">
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column-12 col col-0" style=3D"vertical-align:top;display:inline-table;backg=
round:transparent;table-layout:fixed;font-family:Arial, Helvetica, sans-ser=
if;font-size:12px;color:#383838;max-width:100%;width:100%;width:-webkit-cal=
c(230400px - 48000%);width:calc(230400px - 48000%);min-width:480px;min-widt=
h:-webkit-calc(100%);min-width:calc(100%);" cellspacing=3D"0" cellpadding=
=3D"0">
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nsparent;line-height:18px;padding:10px 30px 0px 30px;" class=3D"elq-button-=
cell cell cell-1">
                                            <div style=3D"text-align:center=
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                                              <div>

                                                <!--[if gte mso 9]>
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